Study Design and Data Analysis

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12 record(s) found




ID Author(s) Title / Description Publication Year
9627 Dorak, M.T.

Epidemiologic Study Designs
Epidemiologic Study Designs
URL: http://www.dorak.info/epi/design.ppt

This presentation by M. Tevfik Dorak of Florida International University was given at a meeting in Bodrum called Clinical Studies & Objective Medicine and discusses aspects of epidemiological study design.

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Source: Florida International University

Keywords:

epidemiology, experimental design, methodology

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20060416
2006
9626 Gay, J.

Clinical Epidemiology & Evidence-Based Medicine Glossary: Clinical Study Design and Methods Terminology
Clinical Epidemiology & Evidence-Based Medicine Glossary: Clinical Study Design and Methods Terminology
URL: http://www.vetmed.wsu.edu/courses-jmgay/glossclinstudy.htm

The following words, synonyms, common abbreviations, and complete definitions are for concepts useful to epidemiology, particularly clinical epidemiology and evidence-based medicine. Some differ from common usage, causing confusion. Applying…

The following words, synonyms, common abbreviations, and complete definitions are for concepts useful to epidemiology, particularly clinical epidemiology and evidence-based medicine. Some differ from common usage, causing confusion. Applying basic clinical epidemiology and evidence-based medicine skills requires understanding these terms within the context of individual patient clinical care. The list the terms is classified into groups according to their usage context and related words rather than being listed alphabetically. These specific terms are important for clinical study and design methods. 

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Source: College of Veterinary Medicine, Washington State University

Keywords:

clinical examination, clinical trials, epidemiology, experimental design, medicine, methodology, terminology

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19980000
1998
9387 Sargeant, J.M., et al

Reporting of methodological features in observational studies of pre-harvest food safety
Reporting of methodological features in observational studies of pre-harvest food safety
URL: http://dx.doi.org/10.1016/j.prevetmed.2010.10.009

Observational studies in pre-harvest food safety may be useful for identifying risk factors and for evaluating potential mitigation strategies to reduce foodborne pathogens. However, there are no structured reporting…

Observational studies in pre-harvest food safety may be useful for identifying risk factors and for evaluating potential mitigation strategies to reduce foodborne pathogens. However, there are no structured reporting guidelines for these types of study designs in livestock species. The objective of this article was to evaluate the reporting of observational studies in the pre-harvest food safety literature using guidelines modified from the human healthcare literature. The researchers identified 100 pre-harvest food safety studies published between 1999 and 2009. Each study was evaluated independently by two reviewers using a structured checklist. 

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Source: Preventative Veterinary Medicine, [Epub ahead of print], Nov. 20, 2010.

Keywords:

control methods, food pathogens, livestock, risk factors, risk reduction

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20101120
2010
9385 Cowling, D.W.; Gardner, I.A.; Johnson, W.O.

Comparison of methods for estimation of individual-level prevalence based on pooled samples
Comparison of methods for estimation of individual-level prevalence based on pooled samples
URL: http://dx.doi.org/10.1016/S0167-5877(98)00131-7

The researchers review frequentist and Bayesian approaches for estimating animal-level disease prevalence using pooled samples obtained by simple random sampling. They determine the preferred approach for different prevalence scenarios…

The researchers review frequentist and Bayesian approaches for estimating animal-level disease prevalence using pooled samples obtained by simple random sampling. They determine the preferred approach for different prevalence scenarios and with varying knowledge about sensitivity and specificity values. 

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Source: Preventive Veterinary Medicine, Vol. 39, No 3, Apr. 9, 1999, p. 211-25.

Keywords:

animal diseases, Bayesian theory, detection limit, diagnostic sensitivity, diagnostic specificity, disease prevalence

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20100409
2010
9194 Centers for Disease Control and Prevention

Timeline: Nationwide Outbreak of Salmonella Enteritidis (SE) Infections Associated with Shell Eggs, United States, 2010
Timeline: Nationwide Outbreak of Salmonella Enteritidis (SE) Infections Associated with Shell Eggs, United States, 2010
URL: http://www.cdc.gov/salmonella/enteritidis/se_timeline_092010.pdf

The United States shell egg recall (2010) has resulted in over 1,600 reported illnesses to date. This Centers for Disease Control and Prevention timeline charts the nationwide outbreak of…

The United States shell egg recall (2010) has resulted in over 1,600 reported illnesses to date. This Centers for Disease Control and Prevention timeline charts the nationwide outbreak of Salmonella enteriditis infections associated with this recall, including dates and details. 

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Source: Centers for Disease Control and Prevention

Keywords:

Centers for Disease Control and Prevention, disease outbreaks, egg products, eggs, food recalls, foodborne illness, Salmonella enteritidis

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20100000
2010
8445 O'Connor, A.M., et al

REFLECT statement: Methods and processes of creating Reporting Guidelines For Randomized Controlled Trials for livestock and food safety
The REFLECT statement: Methods and processes of creating Reporting Guidelines For Randomized Controlled Trials for livestock and food safety
URL: http://dx.doi.org/10.1016/j.prevetmed.2009.10.008

The objective of this project is to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A two-day consensus…

The objective of this project is to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A two-day consensus meeting was held on November 18–19, 2008 in Chicago, IL, USA, to achieve the objective.

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Source: Preventive Veterinary Medicine, Vol. 93, No., Jan. 2010, p. 11-18.

Keywords:

animal health, animal-based foods, livestock, surveys

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20100100
2010
8255 Gardner, I.A.; Stryhn, H.; Lind, P.; Collins, M.T.

Conditional dependence between tests affects the diagnosis and surveillance of animal diseases
Conditional dependence between tests affects the diagnosis and surveillance of animal diseases
URL: http://dx.doi.org/10.1016/S0167-5877(00)00119-7

This study calculates conditional covariances as a measure of dependence between binary tests and shows their relationship. The writers use published data for toxoplasmosis and brucellosis in swine, and…

This study calculates conditional covariances as a measure of dependence between binary tests and shows their relationship. The writers use published data for toxoplasmosis and brucellosis in swine, and Johne’s disease in cattle to illustrate calculation methods and to indicate the likely magnitude of the dependence between serologic tests used for diagnosis and surveillance of animal diseases.

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Source: Preventive Veterinary Medicine, Vol. 45, No. 1-2, May 30, 2000, p. 107-122.

Keywords:

animal diseases, bacteria, Brucella, cattle, monitoring, pathogens, pork, Protozoa, swine, Toxoplasma gondii

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20000530
2000
8247 Branscum, A.J.; Johnson, W.O.; Gardner, I.A.

Estimation of diagnostic-test sensitivity and specificity through Bayesian modeling
Estimation of diagnostic-test sensitivity and specificity through Bayesian modeling
URL: http://dx.doi.org/10.1016/j.prevetmed.2004.12.005

Here, recent Bayesian approaches to estimation (based on cross-sectional sampling designs) of the sensitivity and specificity of one or more diagnostic tests are reviewed. The primary goal is to…

Here, recent Bayesian approaches to estimation (based on cross-sectional sampling designs) of the sensitivity and specificity of one or more diagnostic tests are reviewed. The primary goal is to provide veterinary researchers with a concise presentation of the computational aspects involved in using the Bayesian framework for test evaluation. The authors consider estimation of diagnostic-test sensitivity and specificity in the following settings: (i) one test in one population, (ii) two conditionally independent tests in two or more populations, (iii) two correlated tests in two or more populations, and (iv) three tests in two or more populations, where two tests are correlated but jointly independent of the third test.

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Source: Preventive Veterinary Medicine, Vol. 68, No. 2-4, May 10, 2005, p. 145-163.

Keywords:

animal diseases, animal health, animal-based foods, Bayesian theory, diagnostic sensitivity, diagnostic specificity, population characteristics, pork, Protozoa, statistics, swine, Toxoplasma gondii, viruses

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20050510
2005
8246 Georgiadis, M.P.; Johnson, W.O.; Gardner, I.A.

Sample size determination for estimation of the accuracy of two conditionally independent tests in the absence of a gold standard
Sample size determination for estimation of the accuracy of two conditionally independent tests in the absence of a gold standard
URL: http://dx.doi.org/10.1016/j.prevetmed.2005.04.004

Here, the authors developed an Excel spreadsheet template to calculate sample sizes to estimate sensitivity and specificity with desired precision in the absence of a gold standard. Calculations are…

Here, the authors developed an Excel spreadsheet template to calculate sample sizes to estimate sensitivity and specificity with desired precision in the absence of a gold standard. Calculations are predicated on the use of two conditionally independent tests for screening animals from two populations and are based on the methods produced by a previous study.

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Source: Preventive Veterinary Medicine, Vol. 71, No. 1-2, Sep. 30, 2005, p. 1-10.

Keywords:

animal health, bovine tuberculosis, cattle, diagnostic sensitivity, diagnostic specificity, diagnostic techniques, population characteristics, reference standards, statistics

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20090930
2009
8245 Branscum, A.J.; Johnson, W.O.; Gardner, I.A.

Sample size calculations for disease freedom and prevalence estimation surveys
Sample size calculations for disease freedom and prevalence estimation surveys
URL: http://www3.interscience.wiley.com/journal/112140119/abstract

This study developed a Bayesian approach to sample size calculations for studies designed to estimate disease prevalence that uses a hierarchical model for estimating the proportion of infected clusters…

This study developed a Bayesian approach to sample size calculations for studies designed to estimate disease prevalence that uses a hierarchical model for estimating the proportion of infected clusters (cluster-level prevalence) within a country or region.

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Source: Statistics in Medicine, Vol. 25, No.15, Nov. 5, 2005, p. 2658 - 2674.

Keywords:

animal diseases, bacteria, Bayesian theory, disease prevalence, infection, pathogens, public health, surveys

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20051105
2005
8192 Sargeant, J.M., et al

Methodological Quality Assessment of Review Articles Evaluating Interventions to Improve Microbial Food Safety
Methodological Quality Assessment of Review Articles Evaluating Interventions to Improve Microbial Food Safety
URL: http://www.liebertonline.com/doi/abs/10.1089/fpd.2006.3.447

This article aimed to evaluate 65 review articles published between 2000 and 2005 that addressed the effectiveness of microbial food safety interventions, using criteria for methodological soundness developed in…

This article aimed to evaluate 65 review articles published between 2000 and 2005 that addressed the effectiveness of microbial food safety interventions, using criteria for methodological soundness developed in the medical field.

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Source: Foodborne Pathogens and Disease, Vol. 3, No. 4, Winter 2006, p. 447-456.

Keywords:

control methods, microbiology, risk reduction

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20060000
2006
8182 Centers for Disease Control and Prevention (CDC)

Epidemiologic Case Studies
Epidemiologic Case Studies
URL: http://www2a.cdc.gov/epicasestudies/

These case studies are interactive exercises developed to teach epidemiologic principles and practices. They are based on real-life outbreaks and public health problems and were developed in collaboration with…

These case studies are interactive exercises developed to teach epidemiologic principles and practices. They are based on real-life outbreaks and public health problems and were developed in collaboration with the original investigators and experts from the Centers for Disease Control and Prevention. The case studies require students to apply their epidemiologic knowledge and skills to problems confronted by public health practitioners at the local, state, and national level every day.
Two types of epidemiologic case studies are available. The computer-based case studies can be used as self-study and in the classroom setting. The classroom case studies are primarily for use in a group setting with a knowledgeable instructor.

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Source: Centers for Disease Control and Prevention

Keywords:

case-control studies, disease outbreaks, epidemiology, public health

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